Members: Dr. Dareuosh Shackebaei Dr. Aliashraf Godini Dr. Houshang Najafi Mahvash Hesari Zeynab Mohammadi Laboratory: Heart Physiology Renal Physiology Research Interests and Projects: Effect of acetaminophen on doxorubicin-induced cardiotoxicity in both baseline and ischemia reperfusion condition. Project number: 95569. Study of the protective effect of ethyl acetate fraction of Persian shallot (Allium hirtifolium Boiss) extract on function of the isolated heart of diabetic rats in the baseline and ischemia- reperfusion conditions. Project number: 94590 Evaluation of the protective effects of garlic extract and diazepam on the function of androgen induced hypertrophic heart in rats. Project number: 94455. Effect of diazepam on isolated heart of the dexamethasone treated rats in ischemia and reperfusion. Project number: 92100. Survey the protective effects of Aminoguanidine and Caffeine on acute renal failure induced by Ischemia/ Reperfusion in rat. Survey the protective effects of hydro-alcoholic extract of Malvasylvestris on cisplatin-induced nephrotoxicity in rat. Survey the protective effects of hydro-alcoholic extract of Malvasylvestris on acute renal failure induced by Ischemia/ Reperfusion in rat. Survey the protective effects of hydro-alcoholic extract of Malvasylvestris on gentamicine-induced nephrotoxicity in rat. Survey the protective effects of hydro-alcoholic extract of Malvasylvestris on liver injury induced by renal Ischemia/ Reperfusion in male rat. Langendorff set up (constant pressure & flow) Cardiac Ischemia reperfusion set up in rabbits, rats and mice Animal model in cardiac hypertrophy Tetrazolium staining of myocardium Histopathological evaluation of myocardium Drug perfusion LDH & MDA assessment Effect of different drugs and plant extracts on the process of myocardial hypertrophy Effect of traditional Persian plant extracts on cardiac protection in ischemia-reperfusion injury Cellular and molecular pathways of cardiovascular disorders Different models of Ischemia and toxin induced acute kidney injuries. Remote organe injuries.